PK/PD analysis of biapenem in patients undergoing continuous hemodiafiltration
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چکیده
منابع مشابه
PK/PD analysis of biapenem in patients undergoing continuous hemodiafiltration
BACKGROUND Continuous hemodiafiltration (CHDF) is used as renal replacement therapy for critically ill patients with renal failure, and to treat hypercytokinemia. Since CHDF also clears therapeutic agents, drug pharmacokinetics (PK) should be dependent upon CHDF conditions. Although the antibiotic biapenem (BIPM) is used in patients undergoing CHDF, the optimal therapeutic regimen in such patie...
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Continuous hemofiltration and continuous hemodiafiltration (CHF/CHDF) were developed as continuous renal replacement therapy for patients with severe conditons and has come to be widely performed mainly in critical care, taking the place of intermittent hemodialysis. The membrane pore size of a hemofilter used for CHF/CHDF allows passage of substances ranging from 30,000 to 50,000 Da, and the m...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Health Care and Sciences
سال: 2015
ISSN: 2055-0294
DOI: 10.1186/s40780-015-0031-6